Melatonin to treat confusion in ICU patients
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This Phase 2 trial tests whether melatonin can reduce delirium, a sudden confusion that can happen in the ICU. If you qualify, you may be given melatonin to see if it improves alertness and comfort during an expected longer ICU stay.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and admitted to the intensive care unit (ICU)
- Your care team expects you will stay in the ICU for more than 48 hours
- You have signs of ICU delirium, with an ICDSC score of 4 or higher within the last 48 hours
- You have not taken melatonin in the past 24 hours
- You do not have allergy or known sensitivity to melatonin or the study medicine ingredients
- You are not pregnant or breastfeeding, and you can use enteral medicines (through a tube or by mouth)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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