Melatonin treatment for low-activity delirium in ICU patients
Treatments studied
Part of Mental health clinical trials.
This trial tests whether giving melatonin (or a placebo) can help adults in the intensive care unit who have a specific type of confusion called low-activity delirium. It aims to improve recovery by supporting sleep–wake regulation in the ICU.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 55 years old or older
- You are currently in the ICU and have low-activity delirium right now
- Your delirium is measured as meeting the trial’s score targets from two brief assessments
- You did not have delirium before you were admitted to the ICU
- You are not currently sedated in the ICU
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 2 trial tests whether melatonin can reduce delirium, a sudden confusion that can happen in the ICU. If you qualify, you may be given melatonin to see if it improves alertness and comfort during an expected longer ICU stay.
This trial tests if giving melatonin (a natural sleep hormone) can help prevent delirium (sudden confusion) in older adults who are hospitalized. It may help you if you are 65 or older and admitted to the hospital for general medical care.
This trial tests whether controlled bright light in the ICU can improve confusion and the sleep-wake rhythm in adults who develop delirium. If it works, it may help patients become more clear-minded sooner while they recover in intensive care.
This trial tests if melatonin can improve sleep quality for patients in the intensive care unit (ICU). If you are able to take pills by mouth and are not on a breathing machine, this study might help you rest better.
This study tests if adding a calming medicine called dexmedetomidine to a sleep-promoting routine can help reduce delirium in ICU patients who are awake and on a breathing machine or high-flow oxygen.
This trial tests whether ramelteon, a sleep medicine, can reduce delirium—a sudden confusion problem—in people in the intensive care unit (ICU). If you qualify, it may help you (or your loved one) stay clearer and more comfortable during ICU treatment.
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