Testing mirtazapine for breathing problems in Rett syndrome
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This study tests whether the drug mirtazapine can reduce breathing issues in females with Rett syndrome. Participants must have a confirmed MECP2 mutation and specific breathing dysfunction like breath holding or hyperventilation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Female, aged 5 to 39 years old
- Diagnosed with Rett syndrome (confirmed by genetic test)
- Has breathing problems such as breath holding, hyperventilation, or air swallowing (at least 10 episodes per day)
- On stable medications for at least 4 weeks and stable therapies for 3 months
- Not pregnant, using birth control if sexually active
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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