Optimised valve expansion for aortic stenosis
Part of Heart & circulation clinical trials.
This study looks at two different ways of expanding a new heart valve during a minimally invasive procedure called TAVI. It aims to find out which method gives the best fit and function of the valve in people with severe aortic stenosis (a narrowed heart valve).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are having a TAVI procedure to replace your narrowed aortic valve.
- Your aortic valve problem is due to severe aortic stenosis (the valve doesn't open fully).
- Your valve has a normal 'tricuspid' (three leaflets) or 'bicuspid' (two leaflets) shape.
- You are not having TAVI because a previous artificial valve has failed.
- You are not having TAVI because your own aortic valve is leaking (regurgitation).
- Your heart anatomy must be suitable as judged by the heart team.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study looks at how well the new heart valve works after a TAVI procedure, using pressure measurements to see if blood flow improves. It aims to confirm that the treatment is effective for people with severe aortic stenosis.
This study tests whether a more precise way of aligning the replacement valve during a minimally invasive aortic valve procedure improves outcomes. It may help people with severe aortic stenosis get a longer-lasting, better-functioning valve.
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This trial tests whether expanding the new heart valve in a more symmetric way after TAVI (a procedure to replace a narrowed heart valve) can reduce the risk of blood clots forming on the valve leaflets. It may help keep the new valve working well over time.
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