Comparing new valves for tight aortic valve in enlarged aorta
Part of Heart & circulation clinical trials.
This trial tests two types of replacement heart valves (self-expanding and balloon-expanding) in people who have severe aortic stenosis (tight heart valve) and an enlarged aorta (the main blood vessel from the heart). The goal is to see which valve type works better for these patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe aortic stenosis, meaning your aortic valve area is very small (1 cm2 or less).
- Your heart team has decided you need a transcatheter aortic valve replacement (TAVR).
- Your ascending aorta (the large artery leaving your heart) is between 45 mm and 54 mm wide on a CT scan.
- You are age 65 or older.
- You have not had any past surgery on your aortic valve or aorta, and you do not have pure aortic regurgitation (leaky valve without narrowing).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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