Modified LCH treatment with or without Luvometinib for children
Treatments studied
Part of Blood & lymphatic, Lungs & breathing clinical trials.
This trial tests a new drug called Luvometinib added to a standard chemotherapy regimen for children with Langerhans cell histiocytosis that affects multiple parts of the body. The goal is to see if the combination works better than the standard treatment alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 0–18 years.
- Diagnosed with Langerhans cell histiocytosis (a rare immune cell disorder) confirmed by a biopsy showing specific markers.
- The disease affects more than one body system (like bones, skin, lungs, liver, etc.).
- No previous treatment for this condition.
- Parent or legal guardian must agree to the study and follow all procedures.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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