Clin2
NCT07443020Possibly a fitRecruiting

Fast immune cells for fluid build-up from cancer

Malignant Pleural EffusionMalignant MesotheliomaPleural Effusion, MalignantMetastasis to Pleura

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a treatment using your own immune cells (T cells) to fight cancer that has spread to the lining of the lung and is causing fluid buildup. It may help if other standard treatments have stopped working.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
10 people
Ages
18 years to 79 years
Study type
Interventional

Who can take part

  • You have fluid in your chest from cancer that started in the lung lining or from mesothelioma, and standard treatments have stopped helping.
  • You are 18 to 79 years old.
  • Your heart pumps well (ejection fraction 45% or higher).
  • You can breathe comfortably without extra oxygen after the fluid is drained.
  • You have a good daily activity level (able to do light work or be up and about).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07192900Recruiting· Phase 1
Fast TILs for metastatic cancer with pleural disease

This trial tests a new therapy using your own immune cells (called TILs) to treat cancer that has spread to the lining of the lungs. The goal is to see if these cells can shrink tumors and help you feel better.

Pittsburgh, Pennsylvania
NCT06016179Recruiting· Phase 1
Tocilizumab given through fluid-draining tubes for advanced cancer

This trial tests a drug called tocilizumab, which is given through the tube that drains fluid from your chest or belly. The goal is to see if it can help control cancer-related fluid buildup and improve symptoms.

Pittsburgh, Pennsylvania
NCT06726564Recruiting· Phase 1
Study of MT027 for malignant pleural effusion

This trial tests a new drug called MT027 for people with advanced cancer that has spread to the lining around the lungs (pleura) and caused fluid buildup. The drug targets a marker on cancer cells called B7-H3. It may help control the fluid and the cancer.

Beijing
NCT07510815Recruiting· Phase 1/Phase 2
Immune cell therapy for advanced mesothelioma

This trial tests a new type of immune cell therapy made from donor cells that are trained to target two specific proteins found on mesothelioma tumors. The goal is to see if these cells can safely shrink tumors or slow the disease when given directly into the chest or belly area.

Shenzhen, Guangdong
NCT07766317Not yet recruiting· Phase 1/Phase 2
Personal immune cell therapy for advanced solid tumors

This trial tests a treatment that takes immune cells from your tumor, multiplies them in a lab, and gives them back to you to fight the cancer. It is for people with advanced solid tumors who have tried other treatments or cannot have them.

NCT07260058Not yet recruiting· Phase 1/Phase 2
Immune cell therapy for advanced solid tumors

This trial tests a new immune cell therapy for people with advanced solid tumors of the lung, liver, colon, rectum, or breast. It aims to see if the treatment is safe and can help shrink or control the cancer.

Hear when a new Malignant Pleural Effusion trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.