Targeted radiation before stem cell transplant for blood cancers
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests whether using focused radiation (stereotactic radiotherapy) on areas where blood cancer has spread outside the bone marrow, just before a stem cell transplant, can improve outcomes. It may help patients with blood cancers like leukemia, lymphoma, or myeloma who have these extramedullary lesions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 60 years old.
- You must have a blood cancer diagnosis such as AML, ALL, CML, MDS, lymphoma, or multiple myeloma.
- You must have cancer that has spread outside the bone marrow (called extramedullary disease), confirmed by a biopsy, cytology, or imaging like PET-CT, CT, or MRI.
- You must have a suitable donor and be scheduled to receive a stem cell transplant from a donor (allogeneic HSCT).
- You must be generally well enough with a performance status score of 0 to 2 or KPS > 60%.
- You must not have had a previous stem cell transplant or an active uncontrolled infection.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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