Clin2
NCT07456371Possibly a fitRecruiting

PIC1 injection for relapsed or refractory B-cell lymphoma

Non-Hodgkin Lymphoma

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This trial tests a new treatment called PIC1 for people with certain types of B-cell lymphoma that have come back after treatment or stopped responding. PIC1 is a type of immunotherapy that helps your immune system attack the cancer cells.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
18 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You must be between 18 and 75 years old.
  • You must have been diagnosed with a type of B-cell non-Hodgkin lymphoma, such as diffuse large B-cell lymphoma, mantle cell lymphoma, or others listed by the study team.
  • Your lymphoma must express a protein called CD19 (tested on a biopsy sample).
  • You must have had at least one prior treatment that included an anti-CD20 antibody and a chemotherapy drug called an anthracycline, unless you could not take them.
  • Your cancer must have either come back after a complete response (relapsed) or not responded to treatment (refractory).
  • You must have at least one tumor that can be measured on a scan, and your overall health must be good enough to participate (ECOG score 0 or 1).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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