Testing a new drug for fentanyl overdose
Treatments studied
Part of Injuries & trauma, Pain clinical trials.
This study tests a new drug, CS-1103, to see if it can safely help reverse the effects of fentanyl (a strong opioid) even after a naloxone block. Healthy volunteers who have used opioids before will be given fentanyl and then the study drug, while researchers monitor safety and how the drug works.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 55 years old.
- You must have taken opioids before (like for dental work, pain, or surgery).
- Your body mass index (BMI) must be between 18 and 30, and you must weigh at least 123 pounds (56 kg).
- If you are a woman, you must not be pregnant or breastfeeding.
- You must have healthy kidneys (no kidney disease).
- You must not have any heart disease or other serious health problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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