Pre-surgery optimization vs standard surgery for endometrial cancer
Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.
This study tests whether a three-month program that includes weight-loss medications and hormone therapy before surgery is better than surgery alone for women with early-stage endometrial cancer and severe obesity. The goal is to see if this approach improves surgical outcomes and overall health.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman aged 18 or older.
- You have early-stage endometrial cancer (grade 1 or 2) or a precancerous condition called atypical endometrial hyperplasia.
- Your cancer is only in the uterus and hasn't spread outside it.
- Your body mass index (BMI) is 40 or higher.
- You agree to be randomly assigned to either immediate surgery or a program that starts with a special treatment plan to help you lose weight and improve your health before surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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