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NCT07463183Possibly a fitRecruiting

Study of MK-8690 for moderate to severe ulcerative colitis

Colitis UlcerativeUlcerative Colitis

Part of Digestive system clinical trials.

This trial tests an investigational drug called MK-8690 for people with moderate to severe ulcerative colitis (UC) who haven't responded well to other treatments or can't tolerate them. The study aims to see if the drug can help control UC symptoms safely.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
100 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You must have had ulcerative colitis for at least 3 months.
  • Your UC must be moderate to severe in activity.
  • You must weigh at least 40 kg (about 88 pounds).
  • You must have tried other treatments for UC and they didn't work well, stopped working, or caused problems.
  • You cannot have Crohn's disease or other types of colitis.
  • You cannot have had your colon removed or a colostomy/ileostomy.
  • You must not have active infections like hepatitis B, C, HIV, or tuberculosis.
  • You cannot have a history of cancer (except certain skin cancers) within the past 5 years.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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