Non-invasive predictors of esophageal varices in children
Part of Digestive system clinical trials.
This study looks for ways to predict if a child with portal hypertension (high blood pressure in the liver's blood vessels) has enlarged veins in the esophagus, without needing an endoscopy. It aims to use simple blood tests and spleen size to identify children who may need further monitoring.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be younger than 18 years old.
- You must have a diagnosis of portal hypertension, which can be due to liver disease or other causes.
- You must not be currently bleeding from varices (enlarged veins in the esophagus).
- You must not have had previous variceal bleeding or treatment (like band ligation or sclerotherapy).
- You must not have had prior surgical shunts or TIPS (a procedure to reduce pressure in the liver).
- You must not be taking beta-blockers (like propranolol) for prevention of variceal bleeding.
- You must not have a systemic infection or a blood disorder that affects platelet count or spleen size.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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