Clinical trials
Esophageal Varices clinical trials
Below are recruiting esophageal varices clinical trials, each written for real people, not researchers. We’re tracking 20 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07253090Recruiting
Blood pressure and vein changes after varices treatment
This trial looks at how endoscopic treatment for enlarged veins in the esophagus (from liver disease) affects certain blood pressure readings. If you have cirrhosis and need treatment to prevent bleeding from these veins, you may be able to join.
HangzhouAges 18–80 - NCT06819566RecruitingPhase 2
Preventing bleeding from enlarged veins in the esophagus
This study tests whether tying off high-risk veins in the esophagus before starting a common liver cancer treatment can prevent bleeding. It is for people with liver cancer that has spread but who have never had cancer treatment before.
Seoul, Song-paAges 19–80 - NCT06881082Recruiting
Comparing two banding methods for esophageal varices
This trial compares two different ways of using rubber bands to treat swollen veins in the food pipe (varices) caused by cirrhosis. It aims to find which method is better at preventing first-time bleeding.
Tanta, GharbyeaAges 18 years+ - NCT07774143Recruiting
How fasting time before banding affects bleeding risk
This study looks at whether the length of time you fast before a procedure to treat varices (enlarged veins in the esophagus) affects the chance of bleeding after the procedure. The procedure, called banding, places small rubber bands around the veins to stop or prevent bleeding.
AnyangAges 18 years+ - NCT06594744RecruitingPhase 4
Preventing first bleeding from varices in liver cancer patients
This trial compares two treatments (banding or a medication called carvedilol) to prevent the first episode of bleeding from enlarged veins in the esophagus in people with liver cancer. The goal is to find which approach is safer and more effective.
TaipeiAges 20–90 - NCT06908798Recruiting
Using a stool test to predict varices in cirrhosis
This study checks if a simple stool test (fecal calprotectin) can help predict the presence of enlarged veins in the esophagus (varices) in people with cirrhosis. If successful, this could offer a non-invasive way to screen for this serious complication.
Tanta, GharbyeaAges 18 years+ - NCT06594783RecruitingPhase 4
Preventing varices bleeding with carvedilol and banding
This trial tests whether adding endoscopic banding helps prevent bleeding from enlarged varices in people with cirrhosis who still have high-risk varices despite taking carvedilol.
TaipeiAges 18–90 - NCT06961526Recruiting
Preventing varices bleeding in liver cancer patients on immunotherapy
This trial tests if preventing esophageal varices (swollen veins in the food pipe) can reduce bleeding risk in people with advanced liver cancer who are receiving a combination of two drugs (atezolizumab and bevacizumab). It may help those with good liver function and no high-risk varices at the start.
Tanta, GharbyeaAges 18 years+ - NCT04499898RecruitingPhase 2/Phase 3
Carvedilol vs banding to prevent first bleeding from esophageal veins
This trial compares two ways to prevent bleeding from enlarged veins in the food pipe (esophageal varices) in people with cirrhosis. It tests whether carvedilol (a blood-pressure/heart medicine) works as well as an endoscopic procedure that places small bands to reduce bleeding risk.
TantaAges 18 years+ - NCT07151885Recruiting
Using ultrasound and blood tests to predict varices risk in cirrhosis
This trial tests if a special ultrasound technique combined with liver stiffness and platelet count can predict which patients with cirrhosis have high-risk varices in the esophagus or stomach, potentially reducing the need for repeated endoscopy.
Changchun, JilinAges 18 years+ - NCT06011980Recruiting
Study for treating esophageal variceal bleeding in cirrhosis
This trial tests a treatment for patients with liver cirrhosis who have bleeding from their esophagus or stomach but are currently stable. It aims to help manage bleeding and improve outcomes.
Hanzhou, ZhejiangAges 18–70 - NCT07248722Enrolling by invitation
Pantoprazole after preventive variceal treatment
This trial tests whether a heartburn medication (pantoprazole) helps patients with liver cirrhosis who have had a procedure to treat enlarged veins in the esophagus or stomach. It looks at how well the medicine works when given after this procedure to prevent complications.
Shenyang, LiaoningAges 18 years+ - NCT07122622Recruiting
Spleen stiffness test to check for dangerous veins in the liver
This trial uses a non-invasive ultrasound test to measure spleen stiffness, which may help find problems with blood pressure in the liver and identify enlarged veins that can bleed. It could help avoid more invasive tests.
Roma, ItaliaAges 18 years+ - NCT07358663Recruiting
Portal hypertension esophageal gastric varices treatment study
This study looks at how well treatments work for people with enlarged veins in the esophagus and stomach caused by a condition called portal hypertension. If you have this condition and have had a CT scan and an upper endoscopy (camera down the throat), you may be able to take part to help doctors understand which treatments work best.
ShanghaiAges 18 years+ - NCT01212250Recruiting
Carvedilol to prevent esophagus bleeding in cirrhosis
This trial tests whether carvedilol can prevent the first development of swollen veins (varices) in the esophagus in people with cirrhosis who do not have them yet. It may help lower the risk of future bleeding from those veins.
New Delhi, National Capital Territory of DelhiAges 18–75 - NCT06549673Recruiting
Stopping beta blocker in controlled cirrhosis
This study is checking if it is safe for people with cirrhosis (liver scarring) to stop taking a certain blood pressure medicine (non-selective beta blockers) if their main liver problem is under control. If you've had varices or bleeding in the past and your liver is now stable, this trial will see if you can safely stop the medicine.
SydneyAges 18 years+ - NCT06970509Recruiting
Improving treatment for stomach bleeding from liver disease
This trial studies better ways to use endoscopy and other treatments to stop bleeding in the stomach or esophagus caused by high blood pressure in the liver (portal hypertension). It may help if you have been diagnosed with portal hypertension and have varices (enlarged veins) in your esophagus or stomach.
Guangzhou, GuangdongAges 18 years+ - NCT07163689Recruiting
TIPS for liver disease with portal hypertension
This trial compares patients who have a rare liver condition (porto-sinusoidal vascular disease) with those who have cirrhosis, to see how a procedure called TIPS (a shunt placed in the liver to reduce blood pressure) works for complications like bleeding, fluid buildup, or blood clots.
Amiens, PicardieAges 18 years+ - NCT07521332RecruitingPhase 4
Testing Apixaban to Prevent Bleeding Complications in Cirrhosis
This study tests whether a blood thinner called apixaban can safely prevent dangerous bleeding in people with cirrhosis (liver scarring) who have portal hypertension (high blood pressure in veins leading to the liver). The goal is to see if it reduces bleeding risk without causing excessive bleeding.
Hyderābād, SindhAges 18 years+ - NCT06863519Enrolling by invitation
Testing HVPG to guide variceal bleeding prevention
This study tests whether using a special blood pressure measurement in the liver (called HVPG) can help doctors choose the best endoscopic treatment for people with cirrhosis who have had variceal bleeding. If you've had bleeding from varices, this study aims to make your follow-up care more personalized and effective.
Hangzhou, ZhejiangAges 18–80
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Common questions
- Are there clinical trials for esophageal varices?
- Yes. Clin2 currently lists 20 recruiting esophageal varices studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a esophageal varices trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a esophageal varices trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.