IV paracetamol during emergency abdominal surgery
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether giving paracetamol (Tylenol) through a vein during emergency belly surgery helps keep your blood pressure and heart rate stable. It may be an option for adults who are not critically unstable or have certain serious heart conditions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult needing emergency abdominal surgery (laparotomy).
- Your physical status is classified as ASA I, II, or III (generally healthy to having a serious disease that is not disabling).
- You do not have severe heart problems such as a weak heart pump (ejection fraction below 40%), heart block, irregular heartbeat, or tight heart valve disease.
- You are not currently unstable — meaning your average blood pressure is below 65 or you need medicine to keep it above 65.
- You do not have a high shock index (heart rate divided by systolic blood pressure greater than 1).
- You are not pregnant or breastfeeding, and you have no known allergy to paracetamol.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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