How medications work in children of different weights during surgery
Treatments studied
Part of Hormones & metabolism clinical trials.
This study measures how two common medications—paracetamol (pain reliever) and cefazolin (antibiotic)—move through the body differently in children who are normal weight versus overweight. Researchers will take small blood samples during routine surgery to understand the best doses for each child.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Child is between 2 and 15 years old
- Child is scheduled for minor elective (planned, non-urgent) surgery requiring general anesthesia
- Child will receive either paracetamol or cefazolin as part of standard care during surgery
- An artery or vein is available for safe blood sampling during surgery
- Parent or guardian gives written permission for the child to participate
- Child has no known allergies to paracetamol or cefazolin
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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