Study of EVM18001 for hard-to-treat autoimmune diseases
Part of Brain & nervous system, Cancer, Immune system & allergy, Skin clinical trials.
This trial tests a new treatment, EVM18001, for people with lupus, myasthenia gravis, or systemic sclerosis that hasn't improved with standard therapies. It aims to see if this therapy can help control the disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 70 years old.
- You must have been diagnosed with lupus, myasthenia gravis, or systemic sclerosis for at least 6 months and it must be active despite standard treatments.
- You must have specific blood markers: for lupus, positive ANA, anti-dsDNA, or anti-Smith antibodies; for myasthenia gravis, positive anti-AChR or anti-MuSK antibodies.
- Your bone marrow and major organs (heart, lungs, liver, kidneys) must be working well enough.
- You must not have had certain previous treatments like CAR-T cell therapy or organ transplants.
- You must agree to use effective birth control for 12 months after the last infusion.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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