Thinking and memory after surgery in older adults
Part of Mental health clinical trials.
This study looks at how well older adults think and remember after surgery. It wants to see if there is a link between anesthesia, surgery, and thinking problems later on.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 70 years old or older.
- You are seen in a clinic for older adults having surgery (called the POPS clinic).
- You are scheduled for colorectal or urological surgery with anesthesia expected to last longer than 1 hour.
- You are not only having numbing medicine (regional anesthesia) for your surgery.
- Your surgery is not planned as a day surgery, and you are expected to stay in the hospital for at least 24 hours.
- You are not expected to be kept asleep and on a breathing machine for more than 24 hours after surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether monitoring how deeply you sleep during anesthesia helps prevent confusion and memory problems after surgery. It is for older adults who can give consent and are having a major operation.
This study looks at a redesigned surgical care plan to better support older adults who may have memory or thinking changes after major planned surgery. If you qualify, you would be assessed before surgery and followed after to see whether this approach helps.
This study looks at how brain “metabolomics” (small chemical signals in the brain/body) relate to thinking or mood problems that can happen after surgery in people age 65 and older. It may help doctors understand who is more likely to have these side effects after an operation.
This study looks at how surgery and anesthesia affect memory and thinking in older adults who already have mild memory problems. It compares patients having elective non-cardiac surgery with a similar group who are not having surgery, to see if the surgery itself causes more confusion or memory decline.
This study looks back at information already collected around elective surgery to understand how anesthesia and surgery may affect thinking and memory (sometimes called POCD). It mainly uses records and questionnaires rather than adding a new treatment.
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