Clin2
NCT07480655Possibly a fitRecruiting

CO₂ gap guided treatment for severe injury patients

PolytraumaResuscitation, Trauma Patients

Part of Injuries & trauma clinical trials.

This trial tests if using a carbon dioxide measurement (the 'CO₂ gap') helps doctors give better fluids and care to adults with serious injuries from accidents or violence. It aims to improve recovery in the ICU.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
60 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You have had serious injuries from blunt force (like a car crash) or a penetrating wound (like a stabbing).
  • You are in a state of shock (low blood pressure or signs of poor blood flow).
  • You have not had a chest injury.
  • You do not have a long-term lung condition like COPD, sleep apnea, or similar disease.
  • You do not have sepsis (infection spreading in the blood) causing shock.
  • You are not pregnant.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07179276Recruiting
Testing CO₂ gap to guide septic shock treatment

This trial checks if measuring the carbon dioxide gap (a sign of how well blood is flowing to organs) can help doctors improve treatment for people in septic shock. Septic shock is a severe infection that causes very low blood pressure and organ damage.

Angers
NCT06735872Recruiting
Non-invasive breathing support for broken ribs and low oxygen

This trial tests if non-invasive breathing support (a mask that helps you breathe) can improve lung healing in people with broken ribs from chest trauma who need extra oxygen. It aims to see if this treatment helps avoid the need for a breathing tube and speeds up recovery.

Lyon, Rhône
NCT05828030Recruiting
High-flow oxygen with a face interface versus nasal mask

This trial compares two ways of giving oxygen to people with serious breathing problems after chest trauma. It looks to see whether a high-flow system works better when delivered through a face interface rather than a facial mask, after standard nasal oxygen fails within 72 hours.

Taipei, Taipei
NCT06483984Recruiting
Testing facemasks to remove carbon dioxide in breathing trouble

This trial tests special facemasks that help remove carbon dioxide from the blood during noninvasive breathing support (like a CPAP or BiPAP mask). It is for people who have a sudden breathing problem with high carbon dioxide and low blood pH.

Roma
NCT07839234Enrolling by invitation
Personalized breathing support for lung injury patients

This trial tests a new way to adjust breathing machine settings for people with a lung condition called ARDS. The adjustments are based on detailed monitoring of the heart and lungs, aiming to improve recovery.

Xiamen, Fujian
NCT04962646Recruiting
Breathing extra carbon dioxide during surgery to prevent brain injury

This trial tests whether giving extra carbon dioxide during surgery can reduce the chance of new brain or nervous system injury after surgery for a sudden, life-threatening tear in the big artery (type A aortic dissection). It may help by protecting the brain while the surgical team repairs the artery.

Lund

Hear when a new Polytrauma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.