Breathing extra carbon dioxide during surgery to prevent brain injury
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether giving extra carbon dioxide during surgery can reduce the chance of new brain or nervous system injury after surgery for a sudden, life-threatening tear in the big artery (type A aortic dissection). It may help by protecting the brain while the surgical team repairs the artery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed acute type A aortic dissection.
- Your doctors have decided you will undergo surgical repair.
- Before surgery, you do not have new brain-related symptoms (like weakness on one side, trouble speaking, or a changed level of awareness).
- You do not have a past stroke that left you with lasting nerve problems.
- You should not have had previous heart surgery.
- You must be able to safely have MRI; you also cannot have implants or devices that are not MRI-compatible.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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