Testing facemasks to remove carbon dioxide in breathing trouble
Part of Lungs & breathing clinical trials.
This trial tests special facemasks that help remove carbon dioxide from the blood during noninvasive breathing support (like a CPAP or BiPAP mask). It is for people who have a sudden breathing problem with high carbon dioxide and low blood pH.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have sudden breathing trouble (acute respiratory failure).
- Your carbon dioxide level is high (PaCO2 of 45 mmHg or more) and your blood pH is low (less than 7.35).
- You must be willing to sign a consent form.
- You should not have very slow breathing, need for immediate intubation, very low blood pressure, high lactic acid, recent head surgery, or any condition that prevents a face mask from fitting.
- You must not have conditions that interfere with special monitoring devices (esophageal balloon or EIT belt).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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