SC101 injection for resistant hypertension with kidney disease
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This early-phase trial tests an injection called SC101 into the fat around your kidney. It aims to help lower blood pressure in people whose hypertension is poorly controlled despite multiple medications and who have moderate to severe chronic kidney disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 65 years old.
- You have resistant hypertension (blood pressure stays high despite taking at least three medications, including a water pill, for at least 4 weeks).
- Your kidney function (eGFR) is between 15 and 40.
- You have not had a heart attack, stroke, heart failure, or serious irregular heartbeat in the last 6 months.
- You do not have a single kidney or polycystic kidney disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new way to lower blood pressure by targeting fat tissue around the kidneys. It is for people whose blood pressure remains high despite taking multiple medications.
This trial tests a new medicine, GW906, given as an injection alongside your current blood pressure pills. It aims to help people whose blood pressure is still too high even with one or two medications.
This study looks at a procedure called renal denervation, which uses a device to calm overactive nerves in the kidneys that can drive high blood pressure. It is for people whose blood pressure stays high even with several medications, or who cannot tolerate blood pressure pills.
This study tests a new medicine called HS-10390 to see if it can help people with chronic kidney disease. It might slow down the disease and protect your kidneys.
This Phase 3 trial compares a plan that uses diuretics (water pills) to lower blood pressure more, versus usual blood pressure care, in people with uncontrolled hypertension and moderate-to-severe chronic kidney disease. It may help your blood pressure control while monitoring safety closely because kidney function changes how medicines work.
This trial tests whether keeping blood pressure and cholesterol at lower-than-usual levels can help slow the decline of kidney function in people with advanced chronic kidney disease. If you have moderately to severely reduced kidney function and meet certain blood pressure and cholesterol criteria, you may be able to join.
Hear when a new Chronic Kidney Disease (Stage 3-4) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.