Stronger BP lowering using diuretics in kidney disease
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This Phase 3 trial compares a plan that uses diuretics (water pills) to lower blood pressure more, versus usual blood pressure care, in people with uncontrolled hypertension and moderate-to-severe chronic kidney disease. It may help your blood pressure control while monitoring safety closely because kidney function changes how medicines work.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18 or older (and frailty score 5 or below if age over 80)
- Chronic kidney disease with eGFR between 15 and 44.9
- You take blood pressure medicine that includes an ACE inhibitor or ARB at the highest dose you can tolerate (or you can take other BP meds if ACEi/ARB isn’t tolerated)
- Your clinic blood pressure is high, and it’s confirmed by home readings or 24-hour blood pressure monitoring
- You have no major recent heart or stroke event in the last 3 months
- You are not pregnant, and if you could become pregnant, you can use reliable birth control
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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