Exercise and diabetes drugs for brain health in older adults
Treatments studied
Part of Hormones & metabolism clinical trials.
This trial tests if combining exercise with a diabetes medication (semaglutide) can improve memory and thinking in older adults with type 2 diabetes. You may benefit if you are 65 or older, have high blood sugar, and are not already exercising regularly.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 65 years or older
- You have type 2 diabetes with an A1c of 7% or higher
- You are on metformin or cannot take metformin and qualify for Ontario Drug Benefit
- You are not doing structured resistance exercise more than once a week
- You have not used a GLP-1 drug (like Ozempic) in the last 6 months
- You have no serious memory problems (score >24 on a memory test)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether regular exercise can improve brain health in people with type 2 diabetes. If you have type 2 diabetes, are not on insulin, are inactive, and are between 30 and 75 years old, you may be able to join.
This trial tests whether a special exercise program (with music and multitasking) can help reduce falls and fractures and improve heart health in older adults with diabetes. If you are 65+ and have diabetes, you may be able to join and get free exercise classes.
This study tests whether a home strength-training program using a smartphone app is doable for older adults with type 2 diabetes who also have mild memory problems. You'll do simple exercises at home, and the program may help improve your thinking and glucose control.
This study tests if a special computer-based brain training program can help improve thinking and memory in older adults with diabetes who are at risk for dementia. It might help keep your mind sharp as you age.
This trial tests whether a structured aerobic (heart-pumping) exercise program can improve memory and thinking in older adults who feel memory trouble but have not been diagnosed with dementia. It focuses on people who are “at increased risk” due to common health factors like high blood pressure or diabetes.
This trial tests a structured lifestyle program (more activity and healthier eating) to help prevent or slow memory and thinking problems. It may be helpful if you’re older but not showing major memory impairment, and you can commit to weekly study activities for about 8 months.
Hear when a new Type 2 diabetes trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.