Metabolically armed GPC3 CAR-T cell therapy for advanced liver cancer
Part of Cancer, Digestive system clinical trials.
This trial tests a new type of immune cell therapy called Metabolically Armed GPC3 CAR-T cells (Meta10-GPC3) for people with liver cancer that has come back or spread and cannot be removed by surgery. The cells are designed to target a protein called GPC3 on cancer cells and may help shrink tumors.
Summary written for real people, not researchers, by Clin2.
Who can take part
- 18 to 75 years old
- Liver cancer that has returned or spread and cannot be surgically removed
- At least one measurable tumor and the tumor must have GPC3 protein (more than 25% of tumor cells)
- Good liver function (Child-Pugh class A) and overall health (ECOG 0-1)
- Acceptable blood counts, kidney and liver lab results, and no active serious infections
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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