Study of two drugs for HER2-altered advanced lung cancer
Part of Cancer, Lungs & breathing clinical trials.
This trial tests a combination of two new drugs (SHR-A1811 and AK112) for people with a specific type of advanced lung cancer that has changes in the HER2 gene. It may help those whose cancer has gotten worse after one previous treatment, or who have not yet had any treatment for advanced disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have advanced or metastatic non-small cell lung cancer that cannot be removed with surgery.
- Your tumor has HER2 changes (amplification or overexpression).
- You have not had prior treatment for advanced disease, or you have had only one prior treatment that stopped working.
- You have at least one tumor that can be measured on scans.
- You are in good enough health to perform daily activities (ECOG score 0 or 1).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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