Clin2
NCT07489755Possibly a fitNot yet recruiting

New TGRX-678 pill for chronic-phase CML

Chronic Myelogenous LeukemiaChronic Myelogenous Leukemia - Chronic Phase

Treatments studied

Part of Blood & lymphatic, Cancer clinical trials.

This trial tests a new targeted therapy pill (TGRX-678) for adults with chronic-phase CML who no longer benefit from or cannot tolerate at least three other targeted therapies. The goal is to see if this drug can control the leukemia better.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
180 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have chronic-phase CML and have tried at least 3 TKIs (targeted therapy pills) with poor results or side effects.
  • Your general health is good enough to get around (ECOG 0-2, meaning you can care for yourself).
  • Your blood counts, kidney, liver, and heart tests are within acceptable ranges.
  • You have not used blood transfusions or growth factors recently, and you are not pregnant or planning to become pregnant.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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