A study of a new drug combination for chronic myeloid leukemia
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a new drug combination (HS-10382 plus another drug) for people with chronic myeloid leukemia (CML) whose current treatments have stopped working or caused side effects. It may help if you have a certain type of CML that is not controlled by previous therapies.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 75 years old.
- Your CML must be in the chronic or accelerated phase and have a specific genetic marker (Philadelphia chromosome or BCR-ABL1 gene).
- You must have tried other targeted therapies (called TKIs) that no longer work or cause too many side effects.
- You must be able to take care of yourself (ECOG performance status 0 or 1) and expected to live at least 12 weeks.
- Women must not be pregnant or breastfeeding and must use effective birth control during and for 6 months after the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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