Comparing two procedures for cirrhosis bleeding and enlarged spleen
Treatments studied
Part of Digestive system clinical trials.
This study compares two procedures to treat bleeding from enlarged veins in the esophagus or stomach for people with cirrhosis and an overactive spleen. The goal is to see which approach reduces bleeding risk and improves blood counts over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have cirrhosis (scarring of the liver) with high blood pressure in the vein that carries blood to the liver.
- You have had bleeding from swollen veins in your esophagus or stomach, and it came back after a treatment called banding (EVL).
- Your spleen is overactive, causing low platelets or white blood cells.
- Your liver function is in a good range (Child-Pugh class A or B).
- You are between 18 and 75 years old.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two ways to prevent future bleeding from enlarged veins in the esophagus or stomach in people with liver cirrhosis. One method uses a small tube (called TIPS) to reduce pressure in the liver, and the other combines a banding procedure with medication. The goal is to see which approach works better.
This trial tests a slightly smaller TIPS stent (underdilated) against the standard size to see which is better at preventing another variceal bleed in people with cirrhosis and liver scarring. It aims to find the safest way to lower pressure in the veins while reducing side effects.
This study tests whether treating enlarged veins in the food pipe or stomach (called varices) in a day-care unit, without an overnight hospital stay, is safe and feasible for people with cirrhosis. The treatment aims to prevent these veins from bleeding.
This trial tests a procedure called splenic artery embolization (blocking part of the blood supply to the spleen) to reduce belly fluid buildup in people with advanced liver disease. It may help if your ascites has not improved with standard treatments and you are not a candidate for TIPS.
This study tests a new way to guide a procedure called TIPS, which helps relieve pressure in the liver caused by fluid buildup or bleeding. The new guidance method may make the procedure safer or more precise.
This study tests a surgery (LSD) in people with liver cirrhosis who have had bleeding from enlarged veins in the food pipe or stomach. It looks at whether the surgery helps improve blood fat levels over two years, which might lower future risks.
Hear when a new Liver Cirrhosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.