Clinical trials
Knee Arthropathy clinical trials
Below are recruiting knee arthropathy clinical trials, each written for real people, not researchers. We’re tracking 25 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07575555Recruiting
Lipedema's role in knee arthritis in women
This study compares women with knee arthritis who do or don't have lipedema (a condition causing painful fat buildup, usually in the legs) to understand how lipedema affects knee joint health. Results may help doctors better treat knee arthritis in women with lipedema.
Izmir, İzmirAges 30–65 - NCT05290818Recruiting
Robotic vs standard knee replacement for inner-joint wear
This trial compares robotic-assisted knee replacement with the usual (non-robotic) approach for people with severe arthritis on the inner (medial) side of the knee. It aims to see which method works better for pain and function while matching the right knee anatomy for certain implant types.
Edinburgh, LothianAges 50–75 - NCT06720779Recruiting
Virtual rehab platform for knee replacement patients
This trial tests a virtual rehab platform for people recovering from knee replacement surgery. It may help you do your rehab exercises more easily at the hospital.
Barakaldo, Basque CountryAges 18–85 - NCT04814082Recruiting
Compare two knee implant types for walking and function
This study compares two designs of knee replacement implants to see how they affect walking, function, and outcomes after surgery. You may be randomly assigned to one of the implant types used for your specific, approved knee replacement.
Baltimore, MarylandAges 18–75 - NCT06379321Recruiting
Triathlon Hinge Knee System Study
This study looks at how well the Triathlon Hinge Knee system works for people who need a complex knee replacement. It helps your surgeon know if this implant is a good option for you.
Weston, FloridaAges Any age - NCT06969222Recruiting
Robotic knee replacement study with a special implant
This study tests a robot-assisted knee replacement using a new type of implant designed to move more like a natural knee. It may help people with arthritis or other knee joint problems who need a total knee replacement.
Larissa, ThessalyAges 18–95 - NCT06617871Recruiting
Comparing two ways to align a new knee replacement
This study compares two different techniques (mechanical alignment vs. kinematic alignment) used during knee replacement surgery with a special knee system. It aims to see which technique leads to better results for patients.
Chicago, IllinoisAges 21–79 - NCT05980442Recruiting
Navigation vs robotic-arm assisted knee replacement
This study compares two different high-tech tools used during total knee replacement surgery: one that uses a navigation system (OrthoPilot) and one that uses a robotic arm (MAKO). The goal is to see if one method leads to better results. If you're having a total knee replacement, this trial could help your surgeon choose the best approach.
Ulm, Baden-WurttembergAges 18–90 - NCT05928403Recruiting
Compare knee implant types by how well people return to sport
This study compares three types of knee replacement implants to see how quickly and how well people can return to sports. It may help doctors understand which implant design supports better movement and recovery.
BiarritzAges 18–70 - NCT03869996Recruiting
Fast-track recovery for knee replacement patients
This trial studies a faster recovery “fast-track” plan for people getting their first total knee replacement for arthritis. It may help by getting you back to movement and normal life sooner, while comparing outcomes against usual care.
BolognaAges 18–78 - NCT07647354Recruiting
Mako robotic joint replacement surgery registry study
This study collects information from patients undergoing hip or knee replacement surgery with either traditional or robotic-assisted techniques. Researchers track your recovery and joint function to understand how well these procedures work.
Jacksonville, FloridaAges 18 years+ - NCT05381818Recruiting
Breathing muscle training before joint surgery
This trial tests whether strengthening breathing muscles before total joint surgery can lower the chance of lung complications after the operation. It may help people who already have breathing problems or a history of smoking.
Jacksonville, FloridaAges 18–100 - NCT06955481Recruiting
Navigated knee replacement study for better outcomes
This study tests a computer-guided system for total knee replacement. It aims to see if using the OrthoPilot® navigation system helps improve surgical precision and long-term results.
ŠumperkAges 18–80 - NCT06298721Recruiting
Personalized care to improve knee replacement satisfaction
This study tests a personalized approach to knee replacement surgery designed for people who are at higher risk of being dissatisfied after the procedure. The goal is to see if tailoring care based on patient-reported outcomes can improve satisfaction.
Cleveland, OhioAges 18–80 - NCT06733597Recruiting
Bone density change after knee replacement with or without cement
This study looks at how bone density in the thigh bone changes after knee replacement surgery, comparing two ways of attaching the new joint (with cement or without). It may help people who have normal bone density or early bone thinning but not full osteoporosis.
Madison, WisconsinAges 55 years+ - NCT06181097Recruiting
Negative pressure wound therapy after knee or hip replacement
This study tests whether using a special bandage that applies gentle suction (negative pressure wound therapy) after knee or hip replacement helps incisions heal better. It may reduce wound complications and improve recovery.
Hong KongAges 50 years+ - NCT06182059Recruiting
Pain after knee replacement study
This study looks at long-term pain after total knee replacement surgery. It may help understand why some people have persistent pain and find ways to prevent it.
Monza, Monza BrianzaAges 18–85 - NCT07544264Recruiting
Five-Year Knee Replacement Outcomes Study
This study follows patients who receive a new knee joint replacement for severe knee arthritis or similar conditions. Researchers will track how well the artificial knee works and how patients recover over 5 years to ensure the replacement lasts and improves quality of life.
BolognaAges 50–85 - NCT04924205Recruiting
Smart knee brace rehab versus usual physical therapy
This trial compares recovery after primary knee replacement using a smart knee brace and app versus standard outpatient physical therapy. It may help you understand which rehab approach leads to better comfort and mobility during recovery.
Iowa City, IowaAges 18–100 - NCT06120023Recruiting
Long-term follow-up of the Madison knee replacement system
This study follows patients in France who receive a Madison total knee replacement. It watches how well the knee works and how the patient feels over time, to make sure the implant is safe and effective.
Lyon, RhôneAges 18 years+ - NCT05302934Recruiting
Testing a knee-surgery app and sensor after knee replacement
This trial checks whether a data platform that uses a wearable sensor and a phone app works well for people getting a total knee replacement. It may help make follow-up care more organized and easier by capturing recovery information.
Konstanz, Baden-WurttembergAges 18 years+ - NCT06337123Recruiting
Testing a new knee replacement implant for total knee replacement
This study tests a specific knee replacement implant (the Physica TT Tibial Plate) in people needing a total knee replacement. The goal is to see how well it works and how safe it is.
Forte dei Marmi, LuccaAges 18 years+ - NCT05459948Recruiting
Follow-up study for a primary knee replacement
This study tracks outcomes after a standard (first-time) total knee replacement using the GMK SpheriKA implant. It mainly looks at how well the knee works in everyday life, including activity and self-checks over time.
MérignacAges 18–80 - NCT05112302Enrolling by invitation
Virtual reality during orthopedic anesthesia
This study tests whether using virtual reality during hip or knee surgery (while you’re receiving a nerve block for anesthesia) helps make the experience more comfortable. You’d try the VR during your procedure, and the team will compare outcomes with usual care.
Jackson, FloridaAges 18 years+
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Knee Arthropathy trials by city
Studies with a site in or near these metro areas.
Knee Arthropathy trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for knee arthropathy?
- Yes. Clin2 currently lists 25 recruiting knee arthropathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a knee arthropathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a knee arthropathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.