Red blood cell transfusion to help remove breathing tube
Part of Blood & lymphatic clinical trials.
This study tests whether giving a red blood cell transfusion before removing the breathing tube can help patients who are anemic (low hemoglobin) and at high risk of needing the tube again. The goal is to see if the transfusion improves their chances of breathing on their own successfully.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been on a breathing machine (ventilator) for at least 24 hours.
- Your doctor plans to remove the breathing tube after a successful weaning trial.
- You are at higher risk of needing the tube again because you are over 65, have a heart condition (such as heart failure or irregular heartbeat), or have a lung condition (like COPD, obesity-related breathing problems, or restrictive lung disease).
- Your hemoglobin level (a protein in red blood cells that carries oxygen) was between 7.5 and 9.5 g/dl in the last 48 hours, without active bleeding or a transfusion during that time.
- You do not have conditions that would exclude you, such as a recent heart attack, a muscle or nerve disease causing your breathing problem, an objection to blood transfusions, active bleeding, or a do-not-reintubate order.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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