Study of three drugs before surgery for stage IIB/III acral melanoma
Part of Cancer, Skin clinical trials.
This trial tests a combination of three medicines (pucotenlimab, lenvatinib, and temozolomide) given before surgery to shrink stage IIB or III acral melanoma. The goal is to see if this treatment can improve outcomes for people whose melanoma can be removed by surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have stage IIB or III acral melanoma that can be surgically removed.
- You have at least one tumor that can be measured on scans.
- You are in good general health, with no serious heart, kidney, liver, or blood problems.
- You have not had any previous drug treatment for melanoma.
- You agree to use effective birth control during the study and for 6 months after.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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