Drug combination before surgery for head and neck mucosal melanoma
Part of Cancer clinical trials.
This trial tests a combination of three drugs (pucotenlimab, lenvatinib, and temozolomide) given before surgery for head and neck mucosal melanoma. The goal is to see if this therapy can shrink the tumor and improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 75 years old.
- You must have mucosal melanoma in the head or neck area that can be removed with surgery.
- You should be in generally good health, able to care for yourself and do light activities.
- You must have a tumor sample available for testing (from a previous biopsy or you'll have one taken).
- Your liver, kidney, bone marrow, and heart function need to be within acceptable ranges.
- You must not have had prior treatment with certain immunotherapy drugs (like PD-1 or PD-L1 inhibitors).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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