Methotrexate for knee arthritis with swelling seen on ultrasound
Treatments studied
Part of Bones, joints & muscles clinical trials.
This trial tests if methotrexate (a medicine that reduces inflammation) can improve knee pain and swelling in people with knee osteoarthritis. It is for patients who have signs of synovitis (inflammation inside the joint) that can be seen on an ultrasound.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 40 and 70 years old
- You have had knee pain on most days for at least 6 months, with moderate to severe pain (score of 4 or more out of 10 on a pain scale)
- An ultrasound has shown inflammation (synovitis) in your knee joint
- You do not have other types of arthritis like rheumatoid arthritis
- You have not used steroid injections or pills for your knee in the last 4 weeks
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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