Study of high PEEP in noninvasive ventilation
Part of Lungs & breathing clinical trials.
This study tests whether using higher pressure settings (PEEP) on a noninvasive breathing mask can help people with low oxygen levels. The doctors will measure the pressure inside your esophagus to guide the treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- Your carbon dioxide level (PaCO₂) is 50 mmHg or less.
- Your oxygen level (PaO₂/FiO₂) is 300 or lower, meaning you need extra oxygen.
- Your breathing machine can measure the pressure inside your esophagus (a tube that leads to your stomach).
- Your breathing failure is not caused by heart failure, asthma, or a sudden worsening of COPD.
- You do not have a collapsed lung (pneumothorax).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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