Clin2
NCT07503600Possibly a fitNot yet recruiting

Melatonin with colistin for drug-resistant infections

Multidrug-Resistant Gram-Negative Bacterial InfectionsAntimicrobial Resistance

Treatments studied

Part of Infections clinical trials.

This study tests whether adding melatonin to the antibiotic colistin helps treat serious infections caused by resistant bacteria. It may improve recovery by reducing inflammation and side effects.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
70 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You have a confirmed infection caused by a type of bacteria that does not respond to many antibiotics.
  • You are already receiving the antibiotic colistin through an IV (into a vein).
  • You have a severe infection or sepsis (a life-threatening response to infection).
  • You are not pregnant or breastfeeding.
  • You do not have severe liver disease, end-stage kidney failure, or a terminal illness.
  • You are not currently taking melatonin and have not taken it in the last 48 hours.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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