Managing Pain After Knee Replacement Surgery
Part of Pain clinical trials.
This study looks at how "rebound pain" (increased pain when pain medication wears off) affects long-term pain after total knee replacement. Researchers want to understand this connection and potentially improve pain management strategies for knee surgery patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 years or older
- Have an ASA physical status of I, II, or III (a measure of overall health before surgery)
- Be scheduled for elective (planned) total knee replacement on one knee only
- Plan to receive spinal anesthesia and a peripheral nerve block (numbing injection near the knee)
- Not be taking high doses of opioid pain medications regularly (less than 60 mg morphine equivalent daily, and for less than 3 months)
- Not have significant nerve damage or pain radiating down your leg
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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