Pain relief after spine surgery with two medications
Part of Pain clinical trials.
This study tests a combination of two medications (dexmedetomidine and esketamine) to help manage moderate-to-severe pain after spine surgery. You would receive these drugs through an IV pump that you control to give yourself pain relief as needed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 40 and 79 years old
- You are having planned back or neck surgery expected to last at least 2 hours under general anesthesia
- Your blood pressure is controlled (systolic under 180, diastolic under 110)
- Your heart rate and heart rhythm are stable—no severe slowness, irregular beats, or recent heart attacks
- You do not have schizophrenia, epilepsy, Parkinson's disease, or severe memory problems
- Your heart, liver, and kidneys are working well enough to safely receive anesthesia
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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