Pain Relief After Spine Surgery Using Two Medications
Part of Pain clinical trials.
This study tests whether combining two medications—dexmedetomidine and esketamine—given during and after spine surgery can reduce chronic pain that sometimes develops months or years after surgery. If it works, it could help prevent long-term pain problems for people having back or neck surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 40 and 79 years old
- You are scheduled for elective (planned) cervical, thoracic, or lumbar spine surgery expected to last at least 2 hours
- Your surgery will be done under general anesthesia (you'll be fully asleep)
- After surgery, you will use a patient-controlled pain pump (you press a button to give yourself pain medicine as needed)
- You do not have severe, uncontrolled high blood pressure (above 180/110 mmHg)
- You do not have serious heart problems, including recent heart attack, severe heart failure, dangerous arrhythmias, or severe bradycardia (very slow heartbeat)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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