Drug combination to reduce long-term pain after spine surgery
Part of Pain clinical trials.
This study tests whether combining two medicines, dexmedetomidine and esketamine, during spine surgery can help prevent chronic pain that sometimes continues for months after surgery. If you are having spine surgery and will use a pain pump afterward, this trial might be a good fit for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 40 and 79 years old.
- You are scheduled for spine surgery on your neck, upper back, or lower back, and the surgery is expected to last at least 2 hours.
- You will receive pain medicine through an IV pump you control after surgery.
- You do not have severe heart, liver, or kidney problems, or other serious health conditions that would make the study unsafe for you.
- You are able to communicate with the study team before surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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