Clinical trials
Spinal Surgery clinical trials
Below are recruiting spinal surgery clinical trials, each written for real people, not researchers. We’re tracking 132 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05824338RecruitingEarly Phase 1
Testing ropivacaine spinal anesthesia for lower back surgery
This early study tests whether using ropivacaine (a local numbing medicine) in spinal anesthesia is safe and workable for certain lower back operations. If you qualify, it may help doctors refine anesthesia choices for your type of surgery.
New Westminster, British ColumbiaAges 19–80 - NCT06995690Recruiting
Ketamine to prevent low blood pressure during orthopedic surgery
This study tests if a low dose of ketamine (a pain medicine) given before spinal anesthesia can prevent dangerously low blood pressure during orthopedic surgery. It might help keep your blood pressure steady, making the procedure safer.
CairoAges 18 years+ - NCT07224451Recruiting
Liquid biopsy during spine surgery with blood-brain barrier disruption
This trial tests a technique called 'barrier disrupting fields' during spine surgery to temporarily open the blood-brain barrier. This may allow doctors to collect a liquid biopsy (a blood test that looks for tumor DNA) to better understand spinal tumors.
Ramat GanAges 18 years+ - NCT05714007RecruitingPhase 4
Iron infusion for anemia after spinal deformity surgery
This trial looks at whether a specific iron infusion (ferric derisomaltose) can help treat anemia after spinal deformity surgery. You may be eligible if your blood counts show anemia soon after surgery and it’s likely due to iron deficiency.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06451627Recruiting
Esketamine for better sleep after spinal surgery
This study tests if a low-dose medicine called esketamine (related to ketamine) can help improve sleep after spinal surgery. It is for adults having planned spinal surgery under general anesthesia.
BeijingAges 18–65 - NCT06843174RecruitingPhase 4
Methadone for pain during and after spine surgery
This trial tests if giving a single dose of methadone right before and during spine surgery can help manage pain better. If it works, you might need fewer other pain medicines after surgery.
Toronto, OntarioAges 18–65 - NCT07542470Enrolling by invitationPhase 4
Cold and compression therapy after spinal surgery
This study compares a new cold and compression device (NICE1) to standard care after spinal surgery to see if it reduces pain and swelling. If you're having spine surgery, this trial tests whether keeping the area cold and compressed helps you recover better.
Sarasota, FloridaAges 18 years+ - NCT03553186RecruitingPhase 3
Tranexamic acid to reduce bleeding in spine surgery
This Phase 3 trial tests whether tranexamic acid can reduce bleeding during major spine fusion surgery for adults with scoliosis or spine degeneration. It may help lessen blood loss and the need for transfusions, while monitoring safety.
New York, New YorkAges 18–80 - NCT06466083Recruiting
Thinking changes after spine surgery in older adults
This study looks at why some older adults have confusion or memory changes after spine surgery. It aims to find patterns that could help prevent these problems.
BeijingAges 65–100 - NCT06244264Recruiting
Using your own blood during spine surgery for lung cancer
This study tests the safety and effectiveness of using your own blood (collected before surgery) during spine surgery for lung cancer that has spread to the backbone. It may help people whose spine is unstable or causing nerve problems.
Guangzhou, GuangdongAges 18–75 - NCT07339475Recruiting
Using vein size to predict blood pressure drops in older adults during hip or leg surgery
This study uses an ultrasound to measure the size of a vein in your leg before surgery to see if it can predict a drop in blood pressure during the procedure. If you are over 60 and having planned lower-limb surgery with spinal anesthesia, this non-invasive test might help your doctors prepare for your care.
CairoAges 60 years+ - NCT05253326Recruiting
Relaxing muscle exercises after spine surgery
This trial tests whether a structured “progressive muscle relaxation” routine can reduce pain and help recovery after spine surgery. You may be asked to learn and practice the relaxation steps even if you’ve never done them before.
Istanbul, ÜsküdarAges 18 years+ - NCT04885244Recruiting
Minimally invasive surgery for adult spine bending and misalignment
This trial looks at how well minimally invasive back surgery works for adults with long-lasting spine deformities (like bending or uneven alignment). It aims to measure outcomes using questionnaires and spine X-ray measurements after treatment.
Phoenix, ArizonaAges 18 years+ - NCT07541612Recruiting
Monitoring Spinal Cord Blood Flow During Aortic Surgery
This study tests a non-invasive monitoring device (NIRS) that tracks blood flow to the spinal cord during planned aortic surgery. The goal is to better understand and prevent spinal cord damage that can cause paralysis after major aortic procedures.
Naples, ItalyAges 18 years+ - NCT07218133Recruiting
Ear Stimulation to Reduce Pain After Spine Surgery
This trial tests whether a gentle electrical stimulation delivered through the ear can reduce inflammation and pain after major spinal fusion surgery. If you are having a long spinal fusion, you might be able to join.
St Louis, MissouriAges 18 years+ - NCT03883022Recruiting
Vancomycin powder plus bone graft to prevent spine surgery infection
This trial tests whether placing vancomycin powder and your own bone graft during spine fusion surgery can lower the chance of infection after surgery. It’s meant for people having instrumented spine fusion after other treatments haven’t helped.
TaipeiAges 20 years+ - NCT06080997Recruiting
Patient expectations before spine surgery
This study looks at what patients expect before having spinal surgery. It may help improve how doctors support you before and after the operation.
Køge, Region SjællandAges 18–100 - NCT07348523Recruiting
Comparing two types of back pain blocks after lumbar spine surgery
This trial compares two ways of delivering a pain-blocking injection (erector spinae plane block) after a single-level lower back surgery. The goal is to see which approach provides better pain relief after surgery.
SamsunAges 18–70 - NCT02314988RecruitingPhase 2/Phase 3
Tranexamic acid to reduce bleeding in spine surgery
This trial tests whether tranexamic acid (a medicine that helps blood clot) can reduce blood loss during long spine surgery after an injury. It may help lower the chance of needing transfusions and manage surgical bleeding.
San Francisco, CaliforniaAges 18–80 - NCT04364295Enrolling by invitation
Patients who used SeaSpine products join a global registry
This registry collects information from people who have been treated with at least one SeaSpine product and had standard imaging and symptom surveys before and after surgery. It helps doctors understand outcomes over time and can support future improvements in care.
Durango, ColoradoAges Any age - NCT07211308Recruiting
A study of spinal cord stimulation for chronic leg pain
This trial tests a type of spinal cord stimulation (DTM SCS) for people with chronic leg or foot pain caused by nerve damage (PSPS-T2). It aims to see if this treatment can safely reduce pain and improve daily life.
BrusselsAges Any age - NCT06935201Recruiting
Digital rehab program for spinal stenosis surgery recovery
This study tests a digital, person-centered rehab program to help people recovering from surgery for lumbar spinal stenosis become more physically active. It aims to see if an online program can improve recovery and quality of life after surgery.
StockholmAges 18 years+ - NCT07681648Enrolling by invitationPhase 4
Nerve blocks vs local numbing for lumbar spine surgery
This study compares two types of nerve blocks (a longissimus plane block and a multifidus plane block) to a local numbing injection for pain control during lumbar spine surgery. It aims to find which method works best for patients having back surgery.
Aswān, Aswan GovernorateAges 18–65 - NCT06282770Recruiting
Light therapy belt for lower back pain after spine surgery
This trial tests whether a special light therapy belt can help reduce long-term lower back pain you still have 1 to 5 years after spinal fusion or decompression surgery.
Los Angeles, CaliforniaAges 18–75
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Common questions
- Are there clinical trials for spinal surgery?
- Yes. Clin2 currently lists 132 recruiting spinal surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spinal surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spinal surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.