Drug combo study for better sleep after major surgery
Treatments studied
Part of Mental health clinical trials.
This study tests whether a combination of two medicines, dexmedetomidine and esketamine, can help improve sleep problems after major non-heart surgery. You may be eligible if you are having planned surgery lasting at least one hour and will use a pain pump after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are scheduled for a planned major non-heart surgery that will last at least 60 minutes and finish by 6 PM.
- You will use a patient-controlled pain pump after your surgery.
- Your surgery is not an emergency, not a bladder surgery, and not an organ transplant.
- You do not have serious heart, liver, kidney, or brain conditions, and you are not pregnant or breastfeeding.
- You have not been diagnosed with sleep apnea or are at high risk for it.
- You are not allergic to dexmedetomidine or esketamine.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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