Urea Treatment for Low Sodium Levels From SIAD
Part of Brain & nervous system, Hormones & metabolism clinical trials.
This trial tests whether urea can help treat dangerously low sodium levels in patients with SIAD (a condition where the body retains too much water) who haven't responded to drinking less fluid. Urea is a naturally occurring substance that may help restore normal sodium balance.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with SIAD (a condition causing low blood sodium despite normal fluid balance)
- Your blood sodium level is below 135 mmol/L and your kidneys are retaining water as expected
- You have tried limiting fluids but still have low sodium levels
- Your liver and kidneys work well enough (kidney function at least 45 mL/min/1.73 m²)
- You are not pregnant, breastfeeding, or allergic to urea
- You are not currently taking other sodium-raising medications like vaptans or salt tablets
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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