Clin2
NCT07535762Possibly a fitNot yet recruiting

Chemotherapy combination for untreated peripheral T-cell lymphoma

Peripheral T-Cell Lymphoma (PTCL NOS)Nodal T-follicular Helper Cell LymphomaAnaplastic Large Cell Lymphoma (ALCL) (ALK-1 Negative)

Treatments studied

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This trial tests a combination of four chemotherapy drugs for people with a type of lymphoma called peripheral T-cell lymphoma who have not had treatment before. The goal is to see if this combination can help control the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
36 people
Ages
65 years and older
Study type
Interventional

Who can take part

  • You are 65 years or older.
  • You have been diagnosed with a specific type of peripheral T-cell lymphoma (PTCL) that has not been treated yet.
  • Your cancer does not have a marker called CD30 (a protein on some lymphoma cells).
  • You are generally able to care for yourself (ECOG score 0-2).
  • Your blood counts, liver, and kidney function are within acceptable levels.
  • You have not had chemotherapy, immunotherapy, or radiation for this lymphoma before (except short-term steroids).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07353840Recruiting
Personalized treatment for T-cell lymphoma after first complete remission

This trial tests if giving a tailored treatment after first complete remission can improve outcomes for certain types of peripheral T-cell lymphoma. It is for people who have finished initial standard chemotherapy with a complete response.

Shanghai, Shanghai Municipality
NCT07072221Recruiting
Matching drugs trial for relapsed T-cell lymphoma

This trial tests a combination of three drugs (bendamustine, chidamide, and lenalidomide) for patients with peripheral T-cell lymphoma that has come back or not responded to treatment. It aims to see if this new combination can help when standard treatments have failed.

Suzhou, Jiangsu
NCT05182957Recruiting· Phase 2
Study of anti-PD-1, lenalidomide, and azacitidine for PTCL

This trial tests a combination of three medicines (anti-PD-1, lenalidomide, and azacitidine) for adults with relapsed or refractory peripheral T-cell lymphoma (PTCL) that is measurable or growing. It aims to shrink lymphoma and improve control of the disease when standard treatments haven’t worked or have stopped working.

Suzhou, Jiangsu
NCT04922567Recruiting· Phase 2
Lenalidomide plus CHOP versus CHOP for untreated PTCL

This Phase 2 trial compares two chemotherapy approaches—adding lenalidomide to CHOP versus CHOP alone—for people with untreated peripheral T-cell lymphoma (PTCL). The goal is to see if the added medicine improves response and safety.

Hangzhou, Zhejiang
NCT07730515Recruiting· Phase 1/Phase 2
Study of XNW5004 plus chemo for untreated T-cell lymphoma

This trial tests a new drug called XNW5004 combined with standard chemotherapy for people who have just been diagnosed with peripheral T-cell lymphoma and haven't had treatment yet. The goal is to see if adding XNW5004 helps more than chemotherapy alone.

Shanghai, Shanghai Municipality
NCT07389616Recruiting· Phase 2/Phase 3
Preventing lymphoma return after transplant

This trial tests a combination of two drugs (cidabenamine and azacitidine) to help prevent peripheral T-cell lymphoma from coming back after a donor stem cell transplant. It is for patients who are at high risk of progression and have already had a transplant.

Shanghai, Shanghai Municipality

Hear when a new Peripheral T-Cell Lymphoma (PTCL NOS) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.