Clin2
NCT07537335Possibly a fitNot yet recruiting

Nerve treatment options for knee arthritis pain

Knee OsteoarthristisRadiofrequency AblationNEUROLYSIS

Part of Bones, joints & muscles, Pain clinical trials.

This study compares two minimally invasive procedures—radiofrequency ablation (using heat) and alcohol injections—to see which one better relieves chronic knee pain from osteoarthritis. It may help people who haven't gotten enough relief from standard treatments like physical therapy or medications.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
50 people
Ages
45 years to 80 years
Study type
Interventional

Who can take part

  • You are between 45 and 85 years old.
  • You have had knee pain for at least 6 months due to osteoarthritis.
  • Your knee X-ray shows advanced arthritis (grade 3 or 4).
  • Your pain is at least a 5 on a 0-10 scale.
  • You've tried conservative treatments (e.g., physical therapy, NSAIDs, injections) for at least 3 months without enough relief.
  • You had a temporary nerve block that reduced pain by at least 50% for 24 hours.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06094660Recruiting
Nerve blocking for knee arthritis pain

This study tests two treatments for knee arthritis pain when knee replacement isn't an option: a nerve block using heat (radiofrequency ablation) or a chemical injection (phenol), compared to standard care. It aims to find a better way to reduce pain and improve daily function.

Hoorn, North Holland
NCT06864390Not yet recruiting
Nerve treatment for severe knee arthritis pain

This study compares two ways to treat severe knee pain by blocking pain signals from the knee nerves: one uses radiofrequency (heat) and the other uses a chemical (phenol). The goal is to find which method provides better pain relief for people with advanced knee osteoarthritis who haven't gotten enough relief from other treatments.

NCT06798038Not yet recruiting· Phase 1
Comparing nerve-blocking treatments for knee arthritis pain

This study compares three minimally invasive treatments to reduce knee pain from osteoarthritis. These treatments aim to block the nerves around the knee using alcohol injection, phenol injection, or a technique that uses heat to disable the nerves.

NCT06858228Not yet recruiting
Nerve-blocking treatments for knee arthritis pain

This study compares two minimally invasive treatments for knee pain caused by arthritis. One uses heat to block pain nerves, the other uses a chemical (alcohol) to do the same. It may help if your knee pain has lasted more than 3 months and you haven't had knee surgery.

São Paulo, São Paulo
NCT07835269Not yet recruiting
Predicting knee pain relief from knee nerve treatment

This study is testing a new way to see if a treatment called radiofrequency ablation (which uses heat to quiet pain nerves) might help knee arthritis, using a special brain-scanning technique to predict who responds best.

London, Ontario
NCT07475793Not yet recruiting
Nerve heat therapy for knee arthritis pain

This study tests a treatment that uses radiofrequency (heat) to target specific nerves around the knee to reduce chronic pain from knee osteoarthritis. It may be a good option if you've had knee pain for a long time and haven't responded to other treatments.

Hear when a new Knee Osteoarthristis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.