Nerve Treatment for Severe Knee Arthritis Pain
Part of Bones, joints & muscles, Pain clinical trials.
This study compares two minimally invasive nerve treatments—radiofrequency ablation and alcohol injection—to reduce chronic knee arthritis pain. Both procedures target nerves that carry pain signals from your knee.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 45–85 years
- Chronic knee pain from osteoarthritis (bone-on-bone wear) for at least 6 months
- Moderate-to-severe arthritis on X-rays (Grade 3 or 4)
- Pain score of 5 or higher on a 0–10 scale
- Conservative treatments (physical therapy, anti-inflammatory drugs, or knee injections) have not worked well for at least 3 months
- You responded well to a test nerve block injection (at least 50% pain relief lasting at least 24 hours)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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