Nerve treatment for severe knee arthritis pain
Part of Bones, joints & muscles, Pain clinical trials.
This study compares two ways to treat severe knee pain by blocking pain signals from the knee nerves: one uses radiofrequency (heat) and the other uses a chemical (phenol). The goal is to find which method provides better pain relief for people with advanced knee osteoarthritis who haven't gotten enough relief from other treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with severe (grade 4) knee osteoarthritis based on X-rays.
- You have tried other treatments (like medications, physical therapy, or injections) and they haven't controlled your pain.
- You have not had a knee replacement surgery.
- You do not have a pacemaker or implantable heart defibrillator.
- You do not have an infected knee or an infection throughout your body.
- You are not allergic to the medicines used in the study.
- You do not have a bleeding disorder or take blood-thinning medications (like warfarin or direct oral anticoagulants).
- You do not have a psychiatric illness.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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