Drug-coated balloon for narrowed brain arteries
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests a special balloon catheter coated with a drug (sirolimus) to treat narrowed arteries inside the brain caused by atherosclerosis (plaque buildup). The goal is to keep the artery open and prevent future strokes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18–80 years
- Had symptoms of a narrowed brain artery (like stroke or TIA) in the last 6 months, confirmed on imaging with 70–99% blockage
- The narrowed artery is in specific brain locations: carotid, middle cerebral, basilar, or vertebral artery
- Have at least one risk factor for atherosclerosis (high blood pressure, diabetes, high cholesterol, smoking, etc.)
- Able to take blood-thinning and antiplatelet medications (aspirin, clopidogrel) without allergies or bleeding risk
- No recent stroke, heart attack, brain bleed, or major surgery in the past 2–30 days
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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