Study of tirzepatide for alcohol use disorder
Treatments studied
Part of Mental health clinical trials.
This trial tests if tirzepatide, a diabetes drug, affects brain chemistry linked to alcohol use. Researchers want to see if it can help people with mild-to-moderate alcohol use disorder who also have tried stimulants.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be enrolled in another study (14AA0181) to join this one.
- You are between 21 and 65 years old.
- You have mild-to-moderate alcohol use disorder (per DSM-5).
- You have had at least some experience with stimulant drugs (like cocaine, amphetamines, or prescription stimulants) in the past.
- You have been drinking heavily for at least 2 years (men: 5+ drinks/day on 5+ days/month; women: 4+ drinks/day on 5+ days/month).
- You are not currently seeking treatment for your alcohol use.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if tirzepatide, a medication that helps with appetite and blood sugar, can help people with alcohol use disorder drink less or stop drinking. You would visit the clinic regularly and receive the drug or a placebo.
This study tests whether a weekly injection of tirzepatide (a medicine for weight and blood sugar) combined with cognitive-behavioral therapy (counseling) can help people with alcohol use disorder who are also overweight or obese. By reducing alcohol cravings and supporting weight loss, the treatment aims to improve both drinking and health outcomes.
This trial tests whether a noninvasive brain stimulation treatment called transcranial direct current stimulation may change brain and behavior in people with alcohol use disorder. It may help researchers understand safety and potential effects, especially in people who are stable on treatment and not having seizure or severe mood symptoms.
This trial tests if tirzepatide, a medication that helps with weight and blood sugar, can improve liver health in people with alcohol use disorder who also have fatty liver disease. It aims to reduce liver fat and related risks.
This trial tests how the medication acamprosate affects brain activity in people with moderate to severe alcohol use disorder. It may help researchers understand how this treatment works.
This study tests whether a medication called tirzepatide (a once-weekly injection) can help people reduce their alcohol consumption. It is for people who drink heavily, have a high BMI, and are actively seeking help to drink less.
Hear when a new Alcohol Use Disorder (AUD) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.