Brain Stimulation and Medication Study for Depression
Treatments studied
Part of Mental health clinical trials.
This early-stage study tests a type of magnetic brain stimulation called theta burst stimulation combined with study medications to help treat moderate to severe depression. Researchers want to understand how this combination affects brain communication and may help reduce depressive symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have moderate to severe depression confirmed by a screening questionnaire
- Your current depression medications have been stable for at least one month and will stay the same during the study
- You are not currently receiving TMS, ECT, or ketamine treatments
- You have no history of seizures, epilepsy, brain injury with prolonged unconsciousness, or major neurological conditions
- You are able to safely receive magnetic brain stimulation and can tolerate an MRI scan
- You are not pregnant and have no known allergies to the study medications (d-cycloserine, baclofen, memantine, or lorazepam)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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