Medication combinations for kidney stone stent discomfort
Treatments studied
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests two different doses of medications (tamsulosin and tadalafil) to help with pain and discomfort from a plastic tube (called a DJ stent) placed in your kidney after stone removal surgery. The goal is to find which dose combination works best and is safest.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You had a kidney stone removed by endoscopic surgery (a minimally invasive procedure) and currently have a plastic DJ stent in place
- You have not had prior surgery on your prostate, bladder, or lower urinary tract
- You do not have cancer, diabetes, kidney disease, or a single kidney
- You are not taking certain medications including alpha-blockers, beta-blockers, calcium channel blockers, or PDE5 inhibitors (like sildenafil)
- You do not have heart problems and can attend follow-up visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This early-phase study tests whether taking an anti-inflammatory medicine around the time of ureter stent placement can improve outcomes for people with kidney stones. It looks for participants who are getting a stent after a scope procedure and who can follow strict medication and health rules.
This trial tests a new type of ureteric stent (a tube that helps drain urine from the kidney) against the standard stent. It is open to patients who have had a stent before and need a new one because of kidney stones or cancer pressing on the ureter.
This study tests whether two medications—melatonin (a sleep aid) and solifenacin (a bladder-control medicine)—can reduce uncomfortable symptoms from a temporary plastic tube (ureteral stent) placed in your urinary system during kidney stone treatment. The goal is to find out if these drugs help you feel better while the stent is in place.
This trial compares two types of temporary drainage tubes (stents) placed in the ureter—the tube that carries urine from kidney to bladder—after surgery to remove kidney or ureteral stones. The study measures which stent causes fewer uncomfortable symptoms during the 2-week recovery period.
This study tests whether L-citrulline (a natural amino acid) or tamsulosin (a common blood pressure medication) helps you pass a small kidney stone stuck in your ureter (the tube from kidney to bladder) without surgery. The goal is to compare which medicine works better and is safer.
This trial is looking at whether placing a small tube (stent) in the ureter before a type of keyhole surgery for kidney stones helps with outcomes like pain and success of the procedure. It aims to see if this pre-treatment makes the surgery easier, potentially reducing complications and improving stone removal.
Hear when a new Kidney Stone trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.