Clinical trials
Kidney Stone clinical trials
Below are recruiting kidney stone clinical trials, each written for real people, not researchers. We’re tracking 79 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07101809Recruiting
Comparing two ways to remove kidney stones
This study compares a standard kidney stone removal procedure (ureteroscopy with laser) to a newer suction-based technology. If you have a kidney stone that needs surgery, this trial may help your doctor find the best way to remove it.
Birmingham, AlabamaAges 18 years+ - NCT04430426Enrolling by invitation
Study for kidney stone patients with an AGXT gene change
This study looks at people age 18+ who have a history of calcium oxalate kidney stones and who have a specific AGXT gene change found on genetic testing. It involves following a controlled diet for five days, which may help researchers understand how diet affects kidney stones in this group.
Birmingham, AlabamaAges 18 years+ - NCT07697677Recruiting
Mini versus standard surgery for complex kidney stones
This study compares two ways to surgically remove large or complex kidney stones. It tests whether a less invasive approach works as well as the standard surgery, with the goal of reducing recovery time and complications.
Guangzhou, GuangdongAges 18–70 - NCT05598645Recruiting
Thulium vs holmium laser for kidney stone procedures
This trial compares two types of lasers used during a procedure to remove kidney stones through the urinary tract. It may help you understand which laser works better for clearing stones while keeping the procedure safe.
Thunder Bay, OntarioAges 18 years+ - NCT06330246Recruiting
Study on gut bacteria for calcium kidney stones
This study looks at whether a specific gut bacteria called Oxalobacter formigenes can help people who form calcium oxalate kidney stones. You will eat a controlled diet and provide samples to see how your body handles oxalate, a substance that can lead to stones.
Birmingham, AlabamaAges 18–70 - NCT06436235Recruiting
Kidney stone inflammation study
This study looks at how the body reacts to calcium-based kidney stones. It compares people who have had a calcium-based kidney stone with healthy volunteers to understand inflammation better.
Chicago, IllinoisAges 18–70 - NCT06809582Recruiting
Body position and kidney stone removal results
This study looks at how your body’s position during surgery affects how well kidney stones are cleared. If you have stones ≤2 cm and are having a scope-based kidney stone removal, you may be able to join.
SamsunAges 18 years+ - NCT06989320Recruiting
Oxalate production in calcium oxalate stone formers
This study looks at how the body makes oxalate (a natural substance that can form kidney stones) in people who have had calcium oxalate stones. You will eat a special diet and stop supplements for a short time to help researchers understand stone formation.
Birmingham, AlabamaAges 18–80 - NCT07055282RecruitingEarly Phase 1
SGLT2 inhibitor for kidney stone prevention
This trial tests if a diabetes medication (SGLT2i) can help prevent calcium kidney stones. Researchers want to see if it changes the way your urine absorbs and processes minerals.
Chicago, IllinoisAges 18–70 - NCT07238803Recruiting
Flexible ureteroscopy with dusting for lower kidney stones
This trial tests if using a flexible tube with a laser (FURS) plus special suction (FANS) is better for breaking up and removing stones from the lower part of the kidney. It may help you if you have stones there and are scheduled for a procedure.
ZagazigAges 18 years+ - NCT07272720Recruiting
Shock wave study for single kidney stones (6-15 mm)
This trial tests a new shock wave device to break apart a single kidney stone. It may be a good option if you have one stone between 6 and 15 mm that is not too hard or too far from the skin.
StockholmAges 18 years+ - NCT07159503Enrolling by invitation
Comparing two procedures for 2-4cm kidney stones
This trial compares two methods to remove kidney stones that are 2-4 cm in size: one uses a thin tube through a small cut in your back (VISOR), and the other uses a larger cut (PCNL). The goal is to see which approach works better and has fewer side effects.
Hangzhou, ZhejiangAges 18–80 - NCT06987084Enrolling by invitationEarly Phase 1
Bryophyllum Tea for Kidney Stone Prevention
This study tests whether a special tea made from the Bryophyllum pinnatum plant can help people who get calcium kidney stones. If you've had a stone or high calcium in your urine, this trial may offer a natural option to try.
Montreal, QuebecAges 18–70 - NCT05417568Recruiting
Testing how oxalate responses differ in kidney stone patients
This study looks at how the body reacts to oxalate in people with calcium oxalate kidney stones and in people without kidney stones. It may help researchers understand why some people form stones and how to better prevent them.
Birmingham, AlabamaAges 18–60 - NCT05516472RecruitingEarly Phase 1
Fecal transplant study for people with frequent kidney stones
This trial tests whether transplanting donated stool microbiome (fecal microbiota transplantation) can change gut bacteria and help reduce harm from frequent kidney stones. You would provide urine and stool samples and have follow-up checks to watch for side effects.
Park City, UtahAges 18–69 - NCT06111885RecruitingPhase 2
Study of two diuretics to prevent kidney stones
This trial tests two diuretics (indapamide and chlorthalidone) to see if they reduce the risk of forming new calcium kidney stones. It may help people who have had at least two calcium-based kidney stones in the past 10 years.
BernAges 18 years+ - NCT06210009Recruiting
Can a heart-healthy diet help prevent kidney stones?
This study tests whether a special diet (called DASH, similar to one for high blood pressure) can reduce substances in urine that cause kidney stones. If you have had kidney stones and live in the Birmingham area, this diet might help prevent future stones.
Birmingham, AlabamaAges 19–89 - NCT06331546Recruiting
Gut oxalate absorption in calcium oxalate stone patients
This study looks at how much oxalate (a substance in many foods) gets absorbed by the gut in people who form calcium oxalate kidney stones. You will eat a controlled diet and provide urine and blood samples over a few days.
Birmingham, AlabamaAges 18–70 - NCT06653738RecruitingPhase 3
Testing empagliflozin and diet advice for kidney stone prevention
This trial tests if a medication called empagliflozin, combined with personalized diet advice, can help prevent kidney stones from coming back. It may be an option if you've had two or more kidney stone events in the last 10 years and your stones were mostly calcium-based.
AmiensAges 18 years+ - NCT06944223Recruiting
Citrate and oxalate study for people with or without kidney stones
This study looks at how your body handles citrate and oxalate, two substances related to kidney stones. You can join whether you've had kidney stones or not, as long as your citrate and oxalate levels are not too high or too low.
Chicago, IllinoisAges 18–70 - NCT06996587Recruiting
Robot vs manual scope for kidney stone removal
This trial compares a robotic system to a manual tool for removing kidney stones. It aims to see which method works better for people with normal kidney anatomy.
BeirutAges 18 years+ - NCT07568990Recruiting
Ureteral Access Sheaths for Kidney Stone Removal Surgery
This trial tests different types of tubes (called ureteral access sheaths) used during a minimally invasive kidney stone removal procedure called RIRS. The goal is to see which type works best and causes the least damage to your ureter (the tube that carries urine from your kidney).
Çorum, ÇorumAges 18–75 - NCT05334979Recruiting
Study oxalate and citrate in people with and without kidney stones
This study compares urine levels of oxalate and citrate in adults who have had calcium kidney stones and adults who have never had stones. It may help researchers understand how these urine chemicals relate to stone risk.
Chicago, IllinoisAges 18–70 - NCT05916963RecruitingPhase 3
Testing a water pill to reduce leftover kidney stone fragments
This Phase 3 study tests whether using a “water pill” called furosemide during a flexible scope procedure helps leave fewer kidney-stone fragments behind. It may help reduce the chance of needing additional treatment later.
AngersAges 18–80
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Kidney Stone trials by city
Studies with a site in or near these metro areas.
Kidney Stone trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for kidney stone?
- Yes. Clin2 currently lists 79 recruiting kidney stone studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a kidney stone trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a kidney stone trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.